Tests on human subjective effects doesn't give nearly the accuracy of a chemical reaction, which is what is being suggested.

There really isn't any other way to do it- it's like measuring the degree of mood changing effects of the latest antidepressant- it's averaged out, but never an exact number. The 'scientific' part is just averaging out the reports of many participants. I would also guess that the 'analgesic values' are based on a number of subjective reports from subjects. It is like comparing caffeine to cocaine- sure you could argue for some sort of equivalency, but there are way too many variables and no matter how many cups of coffee you drink, you're never going to get the euphoric feelings of any amount of cocaine. THERE IS NO SCIENTIFICALLY CALCULATED MEASUREMENTS OF EFFECTS OF KRATOM!!! Not to mention the opioids on the right hand side all effect opioid receptors the a very similar way, while kratom has fundamentally different effects on these receptors in the brain. Taking 20+ grams of Kratom is not a good idea, generally there's a ceiling effect after which the Kratom experience becomes less euphoric and more nauseous/dysphoric.Ĭlick to expand.This is a very old thread, but that statement is something I couldn't let go. This is just an estimate however, and it's important that you start with low dosages of Kratom (2-5 grams) and then work your way slowly up, just in case you're allergic to Kratom or if you get a particularly strong batch. Hopefully this helps people put Kratom dosages in perspective, and helps in deciding how much Kratom to take. This makes sense to me, since when I take Hydrocodone I take 20-30 mg to get nice and high, and Hydrocodone is the same strength as Morphine.Ī helpful chart, once again this is all an estimate, Kratom strength does vary.ġ0 grams of Kratom = 5.7 mg Methadone (acute exposure)ġ0 grams of Kratom = 0.5 mg Buprenorphine I typically take 10-15 grams of Kratom at night to get strong sensations of warmth, euphoria, and sedation, which is comparable to a dose of 20-30 mg Morphine.

(Ignoring variations between strains, freshness, etc.) Thus, for every gram of Kratom leaf, there's the equivalent of 2 mg of Morphine. Mitragynine is estimated to be 1/10 the potency of Morphine, while 7-Hydroxymitragynine is 17 times stronger than Morphine. I got the percentages from here: There's likely variations in the percentages of Mitragynine and 7-Hydroxymitragynine between strains. 2% of the alkaloid content is 7-Hydroxymitragynine, so there's 0.1 mg of 7-Hydroxymitragynine per gram of Kratom leaf. Of course there's likely variation in this figure, depending on the strain of Kratom and how fresh it is.Ħ6% of the alkaloid content is Mitragynine, so there's 3.3 mg of Mitragynine per gram of Kratom leaf. Kratom leaves contain roughly 0.5% alkaloids, so for every 1 gram of leaf there's 5 mg of alkaloids.

Kratom and fentanyl bluelight